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Hb A1c ( Glycosylated Hemoglobin )
Rate: Rs. 600
Sample
The blood sample is taken in the EDTA 3 to 4 ml.
Washed RBC or hemolysate is prepared and this is stable 4-7 days at 4C.
Physiology
•Glycohemoglobin is a normal , minor type of hemoglobin.This is blood glucose bound to hemoglobin.In the presence of hyperglycosemia , an increase in the glycohemoglobin causes increase in the Hb A1c.
•Glycosylated hemoglobin reflects average blood glucose level for the 2 to 3 months period before the test.
•glycated hemoglobin concentration reflects the mean blood glucose level concemtration over the last 4-8 weeks.
Interpretation
It is used to monitor the treatment.Its role for the diagnosis is controversial.
Normal
Hb A1c = 4.0—6.7 % of total Hemoglobin.
Hb A1c > 8.1 %( corresponds with glucose >200 mg/dl
Glycated HB is raised as rfelection of hyperglycemia during the life span of RBC.
